There
are nine major types of MD affecting people
of all ages, from infancy to middle age or later. The two
most common types of MD affect children:
Duchenne
muscular dystrophy (DMD)
Becker
muscular dystrophy (BMD)
Both DMD and BMD affect
boys almost exclusively, but in rare cases can also affect
girls. Both Duchenne and Becker muscular dystrophy cause weak
muscles, lack of coordination and progressive disability.
Duchenne
muscular dystrophy (DMD), the most common
type of the disease, is caused by a problem with the gene
that makes a protein called dystrophin. This protein helps
muscle cells keep their shape and strength. Without it, muscles
break down and a person gradually becomes weaker. DMD begins
with muscle loss in the pelvis, upper arms and legs. DMD affects
boys. They may have:
 |
Difficulty
walking, such as being late in learning how to walk
(more than 18 months old), having a waddling gait or
walking on toes or balls of the feet. |
 |
Difficulty
running or jumping caused by weakness in leg muscles.
|
 |
Frequent
falls, stumbling and difficulty climbing stairs. |
 |
Difficulty
standing from a lying or sitting position. |
 |
Reduced
endurance. |
 |
Enlarged
calf muscles. |
 |
Enlarged
calf muscles. |
Symptoms
usually start between ages 2 and 6. By age 10 or 12, kids
with DMD often need to use a wheelchair. The heart may also
be affected, and people with DMD need to be followed closely
by a lung and heart specialist. They can also develop scoliosis
(curvature of the spine) and tightness in their joints. Over
time, even the muscles that control breathing get weaker,
and a person might need a ventilator to breathe. People with
DMD usually do not survive beyond their late teens or early
adulthood.
Becker muscular dystrophy
(BMD), begins with muscle loss in the hips, pelvis, thighs
and shoulders. Becker is basically a milder form of Duchenne
and like DMD, affects boys. Children with BMD may have:
 |
Difficulties
similar to DMD. |
 |
A
waddling gait, perhaps walking on toes or sticking out
the abdomen to balance weak muscles. |
The disease
is very similar to DMD, but its symptoms may start later and
can be less severe. With BMD, symptoms like muscle breakdown
and weakness sometimes don't begin until age 10 or even in
adulthood. People with BMD can also have breathing, heart,
bone, muscle, and joint problems. Many people with BMD can
live long, active lives without using a wheelchair. How long
a person with BMD can live varies depending on the severity
of any breathing and heart problems.
OTHER TYPES OF MUSCULAR DYSTROPHY:
The life expectancy for many of these forms of muscular dystrophy
depends on the degree to which a person's muscles are weakened
as well as how much the heart and lungs are affected.
 |
Emery-Dreifuss
muscular dystrophy (EDMD) typically starts causing symptoms
in late childhood to early teens and sometimes as late
as age 25. EDMD is another form of muscular dystrophy
that affects mostly boys. It involves muscles in the
shoulders, upper arms, and shins, and it often causes
joint problems (joints can become tighter in people
with EDMD). The heart muscle may also be affected. |
 |
Limb-girdle
muscular dystrophy (LGMD) affects boys and girls equally,
weakening muscles in the shoulders and upper arms and
around the hips and thighs. LGMD can begin as early
as childhood or as late as mid-adulthood, and it often
progresses slowly. Over time, a wheelchair might be
necessary to get around. There are many different types
of LGMD, each with its own specific features. |
 |
Facioscapulohumeral
muscular dystrophy (FSHD) can affect both guys and girls,
and it usually begins during the teens or early adulthood.
FSHD affects muscles in the face and shoulders and sometimes
causes weakness in the lower legs. People with this
type of MD might have trouble raising their arms, whistling,
or tightly closing their eyes. How much a person with
this form of muscular dystrophy is affected by the condition
varies from person to person. It can be quite mild in
some people. |
 |
Myotonic
dystrophy (MMD) is a form of muscular dystrophy in which
the muscles have difficulty relaxing. In teens, it can
cause a number of problems, including muscle weakness
and wasting (where the muscles shrink over time), cataracts,
and heart problems. |
 |
Congenital
muscular dystrophy (CMD) is the term for all types of
MD that show signs in babies and young children, although
the MD isn't always diagnosed right away. Like other
forms of MD, CMD involves muscle weakness and poor muscle
tone. Occurring in both girls and boys, it can have
different symptoms. It varies in how severely it affects
people and how quickly or slowly it worsens. In rare
cases, CMD can cause learning disabilities or mental
retardation. |
|