Many
people don't know much about muscular
dystrophy. Yet a quarter of a million kids and adults
are living with the disease, so chances are you may
know someone who has it. Muscular dystrophy (MD) is
a group of rare diseases. It is a genetic disorder that
weakens the muscles that help the body move. They cause
muscle fibers to weaken and break down. People with
MD have incorrect or missing information in their genes,
which prevents them from making the proteins they need
for healthy muscles. MD affects the skeletal or voluntary
muscles that control movement in the arms, legs and
trunk. It also can affect the heart and other involuntary
muscles. These disorders vary in their age of onset,
in severity and in the pattern of which muscles are
affected. All forms of muscular dystrophy, however,
grow worse as muscles progressively degenerate. In some
types of muscular dystrophy, the heart, the gastrointestinal
system, endocrine glands, the skin, the eyes and other
organs may be affected. MD weakens muscles over time,
so children, teens, and adults who have the disease
can gradually lose the ability to do things like walking
or sitting up.
MD is a sex-linked recessive disease.
It typically passes from a mother (who has no symptoms)
to her son. Because MD is genetic, people are born with
the problem - it's not contagious and you can't catch
it from someone who has it. MD passes from parent to
child (genetic) and gets worse over time (progressive).
All of the muscular dystrophies are genetic disorders,
although the types of inheritance vary, and Duchenne
muscular dystrophy, the most common and best known of
the childhood muscular dystrophies, often arises from
new mutations.
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